Vardan a obtenu un doctorat en linguistique du Centre pour le Langage et le Cerveau (Université HSE, Moscou, Russie), avec une spécialisation sur les troubles du langage et de la communication chez les enfants autistes. Il a également effectué un post-doctorat en électroencéphalographie clinique au Seattle Children’s Research Institute (Seattle, WA, États-Unis) dans le laboratoire de Sara Jane Webb, où il a poursuivi ses recherches sur le développement du langage et des fonctions cognitives chez les enfants autistes.
Dans ses travaux de recherche, Vardan utilise de multiples approches et méthodes, telles que l’évaluation comportementale, les approches génétiques (polymorphisme, variations du nombre de copies à l’échelle du génome) et les méthodes neurobiologiques (magnétoencéphalographie, électroencéphalographie, morphométrie cérébrale), afin d’étudier la variabilité des compétences linguistiques ainsi que les mécanismes cérébraux structurels et fonctionnels liés aux troubles du langage chez les enfants autistes.
Les études actuelles de Vardan combinent des approches génétiques, neuroimagerie et comportementales pour comprendre les bases biologiques du langage chez les personnes autistes et leurs parents au premier degré. Ses recherches portent également sur les biomarqueurs des troubles du langage dans l’autisme et la présence de ces biomarqueurs dans les essais cliniques. De plus, ses travaux visent à identifier les marqueurs neuronaux précoces des troubles du langage chez les nourrissons à risque de développer un trouble du spectre de l’autisme, et à évaluer la validité de ces marqueurs pour prédire les compétences linguistiques à long terme chez les enfants qui recevront ultérieurement un diagnostic d’autisme.
Tout au long de sa carrière, Vardan a reçu de nombreux prix de recherche et d’enseignement décernés par plusieurs organisations en Russie, dans l’Union européenne et aux États-Unis. Il a présenté les principaux résultats de ses recherches en Russie, en Allemagne, en France, en Italie, à Singapour, au Canada, aux Émirats arabes unis et aux États-Unis.
Publications:
Arutiunian, V., Buyanova, I., Minnigulova, A., Davydova, E., Pereverzeva, D., Sorokin, A., Tyushkevich, S., Mamokhina, U., Danilina, K., & Dragoy, O. (2025). Left-hemispheric atypicalities in the primary auditory cortex are associated with language comprehension and social skills in school-aged children with Autism Spectrum Disorder.
Cerebral Cortex, 35(3), bhaf055.
https://doi.org/10.1093/cercor/bhaf055
Arutiunian, V., Santhosh, M., Neuhaus, E., Sullivan, C.A.W., Bernier, R.A., Bookheimer, S.Y., Dapretto, M., Geschwind, D.H., Jack, A., McPartland, J.C., van Horn, J.D., Pelphrey, K.A., Gupta, A.R., Webb, S.J., & the ACE GENDAAR Network (2025). A common genetic variant in the Neurexin family member
CNTNAP2 is related to language but not communication skills in youth with Autism Spectrum Disorder.
Autism Research, 18,898–908.
https://doi.org/10.1002/aur.3193
Minnigulova, A., Protopova, M., Dragoy, O., &
Arutiunian, V. (2025). Atypical Social Behavior is Predicted by Overconnectivity Between Salience and Default Mode Networks in Autism Spectrum Disorder.
Journal of Autism and Developmental Disorders, 1–9.
https://doi.org/10.1007/s10803-025-06840-w
Minnigulova, A., Dragoy, O., &
Arutiunian, V. (2025). Atypical segregation of frontoparietal and sensorimotor networks is related to social and executive function impairments in children with ASD.
Brain Imaging and Behavior, 1–10.
https://doi.org/10.1007/s11682-025-01016-7
Minnigulova, A., Karpychev, V., Davydova, E., Pereverzeva, D., Sorokin, A., Tyushkevich, S., Mamokhina, U., Danilina, K., Dragoy, O., &
Arutiunian, V. (2025). Altered thalamotemporal structural connectivity is associated with autistic traits in children with ASD.
Behavioural Brain Research, 481, 115414.
https://doi.org/10.1016/j.bbr.2024.115414
Arutiunian, V., Arcara, G., Buyanova, I., Fedorov, M., Davydova, E., Pereverzeva, D., Sorokin, A., Tyushkevich, S., Mamokhina, U., Danilina, K., & Dragoy, O. (2024). Abnormalities in both stimulus-induced and baseline MEG alpha oscillations in the auditory cortex of children with Autism Spectrum Disorder.
Brain Structure and Function, 229, 1225–1242.
https://doi.org/10.1007/s00429-024-02802-7
Arutiunian, V., Santhosh, M., Neuhaus, E., Borland, H., Tompkins, C., Bernier, R.A., Bookheimer, S.Y., Dapretto, M., Gupta, A.R., Jack, A., Jeste, S., McPartland, J.C., Naples, A., van Horn, J.D., Pelphrey, K.A., & Webb, S.J. (2024). The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives.
Molecular Autism, 15, 19.
https://doi.org/10.1186/s13229-024-00598-1
Samoylov, I., Arcara, G., Buyanova, I., Davydova, E., Pereverzeva, D., Sorokin, A., Tyushkevich, S., Mamokhina, U., Danilina, K., Dragoy, O., & Arutiunian, V. (2024). Altered neural synchronization in response to 2 Hz amplitude-modulated tones in the auditory cortex of children with Autism Spectrum Disorder: An MEG study. International Journal of Psychophysiology, 203, 112405.
Arutiunian, V., Arcara, G., Buyanova, I., Buivolova, O., Davydova, E., Pereverzeva, D., Sorokin, A., Tyushkevich, S., Mamokhina, U., Danilina, K., & Dragoy, O. (2023). Event-Related Desynchronization of MEG Alpha-Band Oscillations during Simultaneous Presentation of Audio and Visual Stimuli in Children with Autism Spectrum Disorder. Brain Sciences, 13, 1313.
Arutiunian, V., Davydova, E., Pereverzeva, D., Sorokin, A., Tyushkevich, S., Mamokhina, U., Danilina, K., & Dragoy, O. (2023). Reduced grey matter volume of amygdala and hippocampus is associated with the severity of autistic symptoms and language abilities in school-aged children with Autism Spectrum Disorder: an exploratory study.
Brain Structure and Function, 228, 1573–1579.
https://doi.org/10.1007/s00429-023-02660-9
Arutiunian, V., Arcara, G., Buyanova, I., Davydova, E., Pereverzeva, D., Sorokin, A., Tyushkevich, S., Mamokhina, U., Danilina, K., & Dragoy, O. (2023). Neuromagnetic 40 Hz Auditory Steady-State Response in the left auditory cortex is related to language comprehension in children with Autism Spectrum Disorder.
Progress in Neuropsychopharmacology and Biological Psychiatry, 122, 110690.
https://doi.org/10.1016/j.pnpbp.2022.110690
Minnigulova, A., Davydova, E., Pereverzeva, D., Sorokin, A., Tyushkevich, S., Mamokhina, U., Danilina, K., Dragoy, O., &
Arutiunian, V. (2023). Corpus callosum organization and its implication to core and co-occurring symptoms of Autism Spectrum Disorder.
Brain Structure and Function, 228, 775–785.
https://doi.org/10.1007/s00429-023-02617-y
Arutiunian, V., Gomozova, M., Minnigulova, A., Davydova, E., Pereverzeva, D., Sorokin, A., Tyushkevich, S., Mamokhina, U., Danilina, K., & Dragoy, O. (2023). Structural brain abnormalities and their association with language impairment in school-aged children with Autism Spectrum Disorder.
Scientific Reports, 13, 1172.
https://doi.org/10.1038/s41598-023-28463-w
Yurchenko, A.,
Arutiunian, V., Shitova, N.M., Bergelson, M., & Dragoy, O. (2023). Registered switching involving lexical-semantic processing in Russian: An ERP study.
Journal of Neurolinguistics, 65, 101111.
https://doi.org/10.1016/j.jneuroling.2022.101111
Arutiunian, V., Arcara, G., Buyanova, I., Gomozova, M., & Dragoy, O. (2022). The age-related changes in 40 Hz Auditory Steady-State Response and sustained Event-Related Fields to the same amplitude-modulated tones in typically developing children: A magnetoencephalography study.
Human Brain Mapping, 43, 5370–5383.
https://doi.org/10.1002/hbm.26013
Arutiunian, V., Lopukhina, A., Minnigulova, A., Shlyakhova, A., Davydova, E., Pereverzeva, D., Sorokin, A., Tyushkevich, S., Mamokhina, U., Danilina, K., & Dragoy, O. (2022). Language Abilities of Russian Primary-School-Aged Children with Autism Spectrum Disorder: Evidence from Comprehensive Assessment.
Journal of Autism and Developmental Disorders, 52, 584–599.
https://doi.org/10.1007/s10803-021-04967-0
Arutiunian, V., Lopukhina, A., Minnigulova, A., Shlyakhova, A., Davydova, E., Pereverzeva, D., Sorokin, A., Tyushkevich, S., Mamokhina, U., Danilina, K., & Dragoy, O. (2021). Expressive and Receptive Language in Russian Primary-School-Aged Children with Autism Spectrum Disorder.
Research in Developmental Disabilities, 117, 104042.
https://doi.org/10.1016/j.ridd.2021.104042
Arutiunian, V., & Lopukhina, A. (2020). The effects of phonological neighborhood density in childhood word production and recognition in Russian are opposite to English.
Journal of Child Language, 47(6), 1244–1262.
https://doi.org/10.1017/S0305000920000112
