The principal aim of this project is to better understand involvement of the superior longitudinal fasciculus (SLF) in visual short-term memory. The SLF is the main white matter track that links the parietal and prefrontal cortices. It is involved in short-term memory and working memory. The main objective of this study is to seek if performance on a visual short-term memory task and modulations of electrophysiological markers during the task are linked to white matter integrity in the superior longitudinal fasciculus in healthy adults. In this study, a visual short-term memory task as well as electroencephalography (EEG), magnetoencephalography (MEG) and diffusion tensor imaging (DTI) will be used. The hypothesis is that visual short-term memory tasks and electrophysiological markers used in this protocol will be linked with the integrity of white matter in the superior longitudinal fasciculus in DTI. This study will include 30 healthy participants aged from 20 to 30 years old and from varying levels of education. A protocol identical to the one used in this project will be used in a research on acute lymphoblastic leukemia (ALL) survivors. The results of this project will help to better understand the link between white matter damage and short-term memory deficits in ALL survivors.
